Hoping to create a powerful mutant he could control, the villainous Mister Sinister engineered Nathan Summers' birth to Scott (Cyclops) Summers and Madelyne Pryor. But when Nathan became infected with the incurable Techno-Organic Virus, his father sent him into the future for treatment.Marvel Source
Nathan lived for decades in the future, becoming a hardened warrior and expert leader. He then returned to the present, vowing to prevent the horrible future he had lived through. He often fights alongside the X-Men, but occasionally works alone or with his own hand-picked teams of mutants.
Energy Pulse: Obvious. Bread and butter boss killer.
Vortex Grenade: Since you're going to be facetanking VG works as bosses won't leave it to chase you down.
Defensive Roll: Necessary for Fearsome Fist to actually work.
Eye for Weakness: More damage.
Bold Aura: More damage.
Telekinetic Shield: 50%+ Damage reduction, mandatory for facetanking for your dodge procs.
Kinetic Repulsion: For AIM because the damage in there is stupid even with dodge and TKS.
Gear
Fearsome Fist: Obvious reasons. That juicy 100% crit for 2 seconds.
Metasensory: One of the best DPS artifacts for Cable by far. The +! compliments every skill, AS helps ENergy Pulse, and the +dmg is hard to beat.
Doom Medallion: Extends the proc duration on FIst. No brainer.
Lifesteal+Fighting X-Gene for huge healing during Fist procs.
Playstyle
Facetank bosses and collect loot. See T4 Red Doom: