As a test subject in the same Weapon X program that had previously given Wolverine his adamantium claws and skeleton, Wade Wilson received a healing factor that prevented his cancer from killing him.Marvel Source
Wade soon escaped the program and became a freelance mercenary using the name Deadpool, working for various criminal organizations. At times he has teamed up with heroes as well, but these attempts at "being a good guy" rarely stick for long.
Wade is mentally unstable, though whether this is a normal state or is caused by his constant state of hyper-regeneration is unknown. One side effect of his mental state is the belief that he is not a real person but actually a character in a comic book.
Right Click- Foot Gougers
A- Stink Bomb or Li'l Deadpool
S- Bodyslie by One
D- Li'l Deadpool or Stink Bomb
F- Power Ups or Superior Healing Factor
G- Superior Healing Factor or Power Ups
The basic build with Deadpool is just to be an unstoppable machine in both the ranged and melee aspects of the hero. The majority of the buffs come from the passives, artifacts, medallions, etc. While you'll just need to focus on a combo using the Left, Right clicks, A and D buttons. While using the S button as a use for transportation.